CS 5124: Algorithms in Bioinformatics

Fall Semester, 2003
Resourses on Protein Scoring Matrices


Paper(s) on (Point Accepted Mutations) PAM Matrices

  1. Dayhoff, M. O., Eck, R. V., and Park, C. M. (1972)
    A Model of Evolutionary Change in Proteins.
    Atlas of Protein Sequence and Structure, Volume 5, 89-99.

  2. Dayhoff, M. O. (1974)
    Computer Analysis of Protein Sequences.
    Federation Proceedings, Volume 33, Number 12, 2314-2316.

  3. Dayhoff, M. O. (1978)
    The Origin and Evolution of Protein Superfamilies.
    Federation Proceedings, Volume 35, Number 10, 2132-2138.

Paper(s) on (Blocks Substitution Matrix) BLOSUM Matrices

  1. Steven Henikoff and Jorja G. Henikoff (1992)
    Amino acid substitution matrices from protein blocks
    Proc Natl Acad Sci U S A 89, pp. 10915-10919.


Internet Resources for PAM, BLOSUM, and Other Protein Scoring Matrices


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